Lung Epithelial Cell Line

Thus as the air sacs of the lungs are approached the respiratory epithelium is formed primarily of cuboidal epithelial cells.

Lung epithelial cell line.

Name tissue cell type disease oganism age ethnicity genes expressed crl 5844 nci h838 h838 lung. It also functions as a barrier to potential. Similar questions and discussions. Human airway epithelial hae cell line nuli 1 was derived from normal lung of a 36 year old patient by dual retroviral infection with hpv 16e6 e7 lxsn pubmed.

Clec213 resemble mammalian pneumocytes type ii. A549 cells are adenocarcinomic human alveolar basal epithelial cells and constitute a cell line that was first developed in 1972 by d. These tall slender cells are anchored on the base of the epithelium which is one layer thick. Clec213 support efficient avian influenza virus growth in vitro.

For lung epithelial cell lines usually they use calu 3 16hbe14o beas 2b and a549 cell lines. 16hbe14o is a human bronchial epithelial cell line isolated from a 1 year old male heart lung patient and immortalized with the origin of replication defective sv40 plasmid psvori. Respiratory epithelium or airway epithelium is a type of ciliated columnar epithelium found lining most of the respiratory tract as respiratory mucosa where it serves to moisten and protect the airways. The cell line retains characteristic features of normal differentiated bronchial epithelial cells including a cobblestone morphology cytokeratin expression the.

The cell lines used in this study are the beas 2b a human bronchial epithelial cell line wi 38 a diploid fibroblast cell line of human fetal lung tissue origin a549 and nci h1703 two human non small cell lung carcinoma nsclc cell lines all of which were collected in our laboratory. Can you help by adding an answer. Through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58 year old caucasian male. Lung cancer and normal cell lines atcc no.

As the airways branch and get smaller the respiratory epithelial cells get shorter. The primary cell cultures are developed from distal human airway epithelial cells of the lower respiratory tract which then develop into the cells which form the surface of the lung s air sacs. Small cell lung cancer homo sapiens 59 years caucasian the cells do not express vasopressin oxytocin or gastrin releasing peptide. The cells are used as models for the study of lung cancer and the development of drug therapies against it.

It is not present in the vocal cords of the larynx or the oropharynx and laryngopharynx where instead the epithelium is stratified squamous.